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Function, expression and polymorphism of human alcohol dehydrogenase 3/glutathionedependent formaldehyde dehydrogenase
(2001-05-02)
Alcohol dehydrogenase 3 (ADH3), identical to glutathione-dependent formaldehyde dehydrogenase, plays a vital role in the defense against formaldehyde through the activity for the spontaneously formed adduct between ...
Ecological impact of antibiotic treatment on human normal microflora
(2013-05-20)
The skin and the mucosal surfaces of humans are colonized with microorganisms which are often referred as the normal microflora. There is a biological balance between the human host and the normal microflora in health. The ...
Synaptic vesicle endocytosis studied in a living synapse
(2000-09-29)
Neurons in the central nervous system communicate by transmitting electrical signals at special sites of contact called synapses. Synapses contain neurotransmitter-filled synaptic vesicles, which fuse with the presynaptic ...
The male predominance in esophageal adenocarcinoma
(2017-02-21)
The incidence of esophageal adenocarcinoma (EAC) has increased rapidly during the past four decades in many Western populations, including North America and Europe. The established etiological factors for EAC include ...
Breast cancer natural history models and risk prediction in mammography screening cohorts
(2022-03-31)
In this thesis, the foundations are laid for a new natural history model for breast cancer—specifically designed to take advantage of detailed screening cohorts. Three diverse applications of this model are then presented. ...
Epidemiological studies on breast cancer risk factors and screening
(2023-09-27)
This thesis aims to enhance cancer prevention by investigating the factors and outcomes associated with false-positive (FP) mammography recalls, as well as understanding the association between breast cancer risk factors ...
Reducing the morbidity of transurethral resection of the prostate based on patient selection, fluid absorption, and blood loss
(2001-10-05)
A higher long-term mortality due to myocardial infarction after TURP, compared to open surgery, irrigating fluid absorption and blood loss, prompted this investigation of whether prostate size has any correlation with ...
Urinary thymine dimer as a biomarker of exposure to ultraviolet radiation
(2013-03-27)
Exposure to ultraviolet radiation (UVR) is associated with all three major forms of skin cancer; squamous cell carcinoma (SCC), basal cell carcinoma (BCC) and cutaneous malignant melanoma (CMM). Different exposure patterns ...
Cardiovascular aspects in mild primary hyperparathyroidism and the outcome after parathyroidectomy
(2011-05-05)
Data on the extent and clinical significance of cardiovascular abnormalities in primary hyperparathyroidism (PHPT) are conflicting. The main objective of this thesis was to evaluate the cardiovascular function in patients ...
Impact of school outdoor environment upon pupils' physical activity and sun exposure across ages and seasons
(2017-10-24)
and physical education (PE) were studied in 196 pupils aged 7-15 years (grades 2, 5, and 8) at four schools in mid-southern Sweden during 5 consecutive days each in September, March and May. Actigraph GT3X+ Activity monitors were used for PA assessments...