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Function, expression and polymorphism of human alcohol dehydrogenase 3/glutathionedependent formaldehyde dehydrogenase
(2001-05-02)
Alcohol dehydrogenase 3 (ADH3), identical to glutathione-dependent formaldehyde dehydrogenase, plays a vital role in the defense against formaldehyde through the activity for the spontaneously formed adduct between ...
Novel statistical methods for genome-wide association summary statistics
(2020-08-20)
A general objective of genetic studies is to understand the genetic basis of complex traits such as height, body mass index (BMI), disease endpoints, etc. Such researches have been facilitated due to the completion of the ...
Natural antibodies against phosphorylcholine as potential protective factors in atherosclerosis, cardiovascular disease and systemic lupus erythematosus
(2009-05-15)
Atherosclerosis is the most important contributor to cardiovascular disease (CVD). Although it was initially considered as a bland lipid storage disease, processes of inflammation and autoimmunity are now considered to ...