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Urinary thymine dimer as a biomarker of exposure to ultraviolet radiation
(2013-03-27)
Exposure to ultraviolet radiation (UVR) is associated with all three major forms of skin cancer; squamous cell carcinoma (SCC), basal cell carcinoma (BCC) and cutaneous malignant melanoma (CMM). Different exposure patterns ...
The anterior chamber of the eye as an islet transplantation site in type-2 diabetes
(2023-08-31)
Diabetes mellitus is a chronic disease, one of the leading causes of death and a
consistent financial burden globally. It occurs when insulin is insufficient for
glucose homeostasis. Pancreatic islet transplantation drew ...
SOX in development and disease
(2018-04-26)
As stem cells are needed not only to build our bodies during development, but also to maintain tissue function during adulthood, it is of great importance to the organism to maintain their integrity. However, stem cells ...
On the origin of ACPA : exploring the role of P. gingivalis in the development of rheumatoid arthritis
(2019-11-22)
Rheumatoid Arthritis (RA) is a systemic autoimmune disease characterized by chronic synovial inflammation, joint destruction, and the presence of anti-citrullinated protein autoantibodies (ACPA) in a majority of patients. ...
Hitting the right targets : a study of molecular mediators of sensitivity to novel potential targeted therapies in cutaneous malignant melanoma
(2020-04-24)
Cutaneous malignant melanoma (CMM) is the deadliest form of skin cancer with a 5-year overall survival (OS) rate of less than 10% among patients diagnosed with disseminated disease. During the past decade the emergence and ...
Vaccination against Her2/neu : expressing cancer using chimeric virus-like particles
(2009-04-24)
Thanks to the development of vaccines, children are these days protected
against infectious diseases like polio, diphtheria and tetanus simply by
receiving a few injections. Imagine a scenario where these injections
would ...