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Epidemiological studies of host susceptibility in malignant lymphomas and colorectal cancer
(2001-03-16)
The aim of this thesis was to investigate the role of host susceptibility in malignant lymphomas and colorectal cancer. Specifically, the associations between infection and malignant lymphomas, skin cancer and survival ...
The matter of white and gray matter in cognitive impairment
(2017-08-03)
Cognitive impairment spans from minor subjective cognitive impairment to disabling dementia. Many biomarkers have been developed to monitor different aspects of cognitive impairment. Magnetic resonance imaging is the most ...
A novel drug and device in anesthesia : with focus on breathing and upper airway physiology
(2018-04-12)
Anesthesia-related airway complications are associated with hypoxia due to inability to secure or maintain the airway with subsequent insufficient ventilation and gas exchange. This thesis has explored the impact on airway ...
Detecting novel effects of exercise or AMPK activation in human skeletal muscle
(2018-04-24)
Cardiovascular and metabolic disorders are among the main causes of death today. Regular exercise can prevent and treat these chronic diseases. A molecule at the center of exercise adaptations in skeletal muscle is adenosine ...
Homelessness and health : analysis of mortality and morbidity from a gender perspective
(2009-03-13)
younger homeless women had the highest risk (RR 2.2). Alcohol use disorders were equally common among homeless men and women, but women had more drug use disorders (RR 1.3). Women had a higher risk of schizophrenia (RR 2.8), and personality disorders (RR 2.7...
Novel approaches for cancer immunotherapy
(2008-05-22)
Cancer immunotherapy, i.e. activation of the patient s own immune system to combat cancer, represents a treatment strategy which is being clinically tested to complement surgery, radiotherapy and chemotherapy the current ...
Aspects of low anterior resection syndrome : prevalence, risk factors and treatment
(2022-03-29)
and 7 of 15 subscales on EORTC QLQ-C30. This study was the first RCT evaluating TAI as treatment for major LARS and concluded that TAI reduces symptoms of LARS with improved QoL....
Potential overtreatment during life-limiting illness and end of life in older adults
(2023-10-11)
decedents had an average 1.7 unplanned hospitalisations during their last year of life, which corresponded to an incidence rate of 175 per 100 person-years. Those with a cancer trajectory had the highest incidence rate at 231 per 100 patient-years, whereas...