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Epidemiology of blood-borne viral infections : with special reference to Central America
(2000-05-04)
Viral diseases transmitted through blood and/or blood products continue to be a major health problem in developing countries. Much less is known about the distribution and transmission routes in these countries in development. ...
Hemodynamics, echocardiography, and biomarkers in different heart failure phenotypes
(2020-02-12)
Background: Heart failure (HF) is a major health problem affecting millions of patients worldwide and is associated with impaired quality of life and poor prognosis. Different approaches including invasive and non-invasive ...
Consequences of outsourcing referrals for radiological examinations
(2016-11-14)
Background: Demands for ever more effective healthcare and care accessibility for all patients continue to increase the workload in diagnostic radiology departments. Along with rapid developments in imaging technology which ...
Costs and consequences in perioperative care : analytic models in studies on pain treatment and on haemodynamic optimization of elderly patients
(2011-01-20)
Background: Because resources are scarce in health care, costs and consequences of new interventions must be assessed to support informed policy decisions.
This thesis analyses the cost-effectiveness of advanced ...
Biomarkers and outcome in children with hypoxic ischemic encephalopathy
(2021-11-04)
Approximately 1-6 per 1000 born infants will develop hypoxic-ischemic encephalopathy (HIE) with significant associated mortality and morbidity. For the past 45 years, severity of HIE has been stratified into mild, moderate, ...
Expression, recognition and usage of laminin-8 (a4b1g1, Lm-411) by monocytes and neutrophils
(2004-09-17)
Laminins (LNs) are a family of large alphabetagamma heterotrimeric glycoproteins found in all basement membranes (BMs). They are expressed in a tissue- and developmental stagespecific manner and implicated in vital cellular ...
Optimization of pediatrics antiretroviral treatment outcomes among HIV infected children in Ethiopia
(2019-12-11)
Ending the HIV/AIDS epidemic by 2030 is a global agenda. To meet this global goal, having safe and effective antiretroviral therapy is a key requirement. In Ethiopia, the safety and efficacy of combination antiretroviral ...
Long-term outcome after hypothermia-treated hypoxic-ischaemic encephalopathy
(2022-05-13)
Hypoxic-ischaemic encephalopathy (HIE) is a major cause of acquired brain injury in newborn infants. It is a potentially life-threatening condition that leaves survivors at substantial risk of life-long debilitating sequelae ...
Pathophysiology in postterm pregnancy : epidemiology, risk factors and cervical ripening
(2012-05-07)
Background: Postterm pregnancy, defined as a pregnancy of 42 or more completed weeks of gestation, occurs in approximately 5-10 % of all pregnancies. The condition is associated with increased maternal and fetal morbidity ...
The pathophysiological roles of kynurenic acid and cytokines in psychiatric illness
(2011-09-07)
Kynurenic acid is an astrocyte-derived tryptophan metabolite and a marker of neuroinflammation that antagonizes N-metyl-D-aspartate (NMDA) and α7 nicotinic acetylcholine receptors in the brain. Increased levels have been found in the cerebrospinal...