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Hemodynamics, echocardiography, and biomarkers in different heart failure phenotypes
(2020-02-12)
Background: Heart failure (HF) is a major health problem affecting millions of patients worldwide and is associated with impaired quality of life and poor prognosis. Different approaches including invasive and non-invasive ...
Glucocorticoid receptor function : interactions, mutants and ligand responses
(2008-05-08)
The protein that is investigated in this thesis is the glucocorticoid
receptor (GR), which belongs to the nuclear hormone receptor superfamily
of ligand activated transcription factors. The nuclear receptors share
three ...
Effects of cigarettes, e-cigarettes and Swedish snus on vascular function
(2018-07-17)
Cigarette smoking is considered one of the leading causes of preventable morbidity and premature death worldwide. A large portion of this is attributable to cardiovascular disease such as ischemic heart disease and stroke. ...
Characterization of B cell response alterations resulting from ablation of IκBNS expression
(2020-08-07)
The immune system is a sophisticated organization of cells and tissues that cooperate in safeguarding the integrity of our body by eliminating internal and external threats. Vaccines are the most impactful medical intervention ...