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Structural studies of saccharopine reductase and purple acid phosphatase
(2000-09-01)
Lysine is synthesised in two different ways in living organisms, either by the diaminopimelate pathway or the [alpha]-aminoadipate pathway. These routes belong to the aspartate and the glutamate family of amino acid ...
Functions of integrin receptors in extravascular neutrophil migration and respiratory burst
(2000-09-01)
[beta]1 integrin significantly reduced the neutrophil migration velocity (from 14.7 ± 1.4 [my]m/min to 3.9 ± 0.9 [my]m/min), whereas blockage of fibronectin binding [alpha]4[beta]1 and [alpha]5[beta]1 integrins was without effect on neutrophil migration...
Signal processing approaches on otoacoustic emissions
(2000-09-29)
The recent achievement on the measurement of otoacoustic emissions (OAEs) is based on a novel technical development of digital signal processing. OAEs measured in the external ear canal are normal by-products of the active ...
Aspects on extracorporeal life support for severe acute respiratory failure with special reference to the influenza A/H1N1 2009 pandemic
(2016-11-03)
. The probability of correctly classifying patients with this score was 75%, where a score of 4.5 was the most appropriate cutoff for prediction of mortality risk. In the external validation group, the score had a good capacity to distinguish survivors from non...
Understanding structure and function of membrane protein transporters
(2008-11-28)
Membrane protein transporters are important proteins in the cell, as they maintain different solutes and metabolites at a stable concentration. Numerous diseases can be linked to malfunctioning transporters, which makes ...
MHC-class I restricted peptide-based immunomodulation of CD8+ T and NK cells
(2012-09-06)
The main aims of the immune system are to protect the host from potential threats by distinguishing self from non-self and altered-self. T cells and NK cells play a key role in the identification and elimination of threats ...
Chemical genetics and immunomodulation in Salmonella enterica serovar typhimurium infection
(2015-04-08)
Salmonella sp. are versatile bacteria that survive and replicate in a plethora of environmental
niches and hosts, including humans. The illnesses caused by various serovars in humans
range from mild gastroenteritis to ...
Functional and genetic studies in type 2 diabetes and obesity
(2013-11-14)
Type 2 diabetes (T2D) and obesity are highly prevalent disorders reflecting a complex interplay of genetics, epigenetics, and environment. They constitute serious health problems and lead to significant morbidity and ...
Using enriched quality register data for health care evaluation : examples from rheumatoid arthritis
(2014-09-24)
Swedish registers have for decades successfully been used for medica research, enabling long-term follow-up of large patient cohorts using observational designs. With a tax funded health care system and the use of a personal ...
Body perception and brain plasticity in blind and sighted individuals
(2023-04-28)
Lack of vision is associated with large-scale brain plasticity. Vision, touch, proprioception, interoception, and other sensory modalities are thought to play a vital role in developing and maintaining bodily awareness. ...