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HIV-1 and HIV-2 infections in Guinea-Bissau, West Africa : studies of immune responses, prevailing viruses and epidemiological trends
(1999-09-17)
to HIV-1-infected individuals and that the viral setpoint after primary infection was 28-fold lower for HIV-2 as compared to HIV-1. The plasma viral load was inversely correlated to CD4+T-lymphocyte levels for both HIV-1 and HIV-2. HIV-1 and HIV-2 dually...
Signal processing approaches on otoacoustic emissions
(2000-09-29)
The recent achievement on the measurement of otoacoustic emissions (OAEs) is based on a novel technical development of digital signal processing. OAEs measured in the external ear canal are normal by-products of the active ...
p53 guardian of the genome and target for improved treatment of leukemia
(2007-03-02)
P53 acts in several cellular processes as cell cycle checkpoints, DNA
repair senescence and the surveillance of genomic integrity. Wt p53
inhibits cancer processes by causing cell cycle arrest and apoptosis. P53
is ...
Modelling depression in animals and the potential antidepressant effect of histaminergic modulation
(2015-05-22)
Depression is at the top position for "years lived with disability" (Smith, 2014). Its aetiology
is unknown, but the pathogenesis implicates changes in glutamatergic neuronal plasticity.
Glutamatergic plasticity likely ...
Plasma cell malignancies in Sweden : subgroup descriptions and regional outcomes for multiple myeloma
(2022-04-13)
Plasma cell disorders appear in various forms such as aggressive plasma cell leukemia (PCL), typical symptomatic multiple myeloma (MM), non-symptomatic smouldering multiple myeloma (SMM) and solitary plasmacytoma (SP). The ...
The neural control of rhythmic motor sequences
(2010-10-29)
Sequence learning is one of the most important functions of the motor system since almost every advanced motor skill consists of many component movements that need to be executed in sequential order. For successful performance ...
Screening for abdominal aortic aneurysm
(2014-09-19)
Abdominal Aortic Aneurysm (AAA) is a common disease with a prevalence of 1.5-2.0%
in 65-year old men in Sweden. The risk of having AAA is increased with smoking, high
age, family history of AAA and cardiovascular disease. ...
Human colorectal cancer : experimental staging and therapeutics
(2007-04-06)
Colorectal cancer is the third most common cause of death in cancer
worldwide and approximately one million individuals are diagnosed yearly.
Surgery is the primary cure, and if that s not feasible, only palliative
therapy ...
Gene expression profiling in periodontitis
(2015-02-06)
in a large number of gingival biopsies both from patients with periodontitis and healthy control subjects. Among the several genes that were significantly up- or down-regulated in periodontitis, the two most differentially expressed were mucin 4 (MUC4...
Improved diagnosis and management of sepsis and bloodstream infection
(2022-11-08)
Sepsis is a severe organ dysfunction triggered by infections, and a leading cause of hospitalization and death. Concurrent bloodstream infection (BSI) is common and around one third of sepsis patients have positive blood ...