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Human colorectal cancer : experimental staging and therapeutics
(2007-04-06)
Colorectal cancer is the third most common cause of death in cancer
worldwide and approximately one million individuals are diagnosed yearly.
Surgery is the primary cure, and if that s not feasible, only palliative
therapy ...
Complement mediated synapse elimination in schizophrenia
(2023-02-23)
Schizophrenia (SCZ) is a devastating psychiatric disorder with a typically age of onset in late adolescence. The heritability is estimated to be in between 60-80% and large-scale genome-wide studies have revealed a prominent ...
Mechanisms and regulation of the polyphosphate/factor XII-driven contact system in thrombosis and hemostasis
(2016-10-03)
Blood coagulation leading to fibrin formation is essential to prevent loss of blood
(hemostasis), but can also contribute to occlusion of vessels (thrombosis). Thrombosis causes
pulmonary embolism, myocardial infarction ...
Aspects of arterial wall healing : re-endothelialization, intimal hyperplasia and vascular remodeling
(2019-05-08)
Cardiovascular disease is the leading cause of mortality in the world. Despite prevention, the need for interventions remains high. Patients with type 2 diabetes mellitus have an increased cardiovascular burden and are at ...