Search
Now showing items 1-10 of 15
Adrenergic control of small intestinal motility and blood flow : an experimental study in rat and man
(1998-12-01)
Small intestinal motility in the fasted state is characterized by migrating motor complexes (MMCs). Both animals and man exhibit the MMC, which consists of periods of regular contractions, i.e. activity fronts, that migrate ...
Survival after different forms of bystander cardiopulmonary resuscitation in out-of-hospital cardiac arrest : ‛to breathe or not to breathe?’
(2019-10-31)
and the last guideline period. Adjusted OR for 30-day survival was 2.6 (95 % CI, 2.4–2.9) for S-CPR and 2.0 (95 % CI, 1.8–2.3) for CO-CPR, in comparison with no CPR. S-CPR was superior to CO-CPR (adjusted OR, 1.2; 95 % CI, 1.1–1.4). In Study III we aimed...
Perioperative risk factors and outcomes
(2020-11-24)
Perioperative complications is an increasing issue worldwide, as surgical volume continues to grow. Myocardial and kidney injury, and myocardial infarction (MI), are known complications in non-cardiac surgery. Hemodynamic ...
Robot-assisted laparoscopy and sentinel node biopsy in high risk endometrial cancer
(2018-11-15)
Surgery is standard treatment for early stage endometrial cancer (EC), the most common gynaecological malignancy in developed countries. Traditionally, surgery has been performed by laparotomy (LT). Comprehensive surgical ...
Optic nerve hypoplasia in children : prevalence, associated disorders and genetic causes
(2018-08-10)
Optic nerve hypoplasia (ONH) is a congenital ocular malformation with a thin optic nerve in one or both eyes. ONH has been associated with neurodevelopmental disorders and pituitary dysfunction, but the prevalence of these ...
Inflammation and cytokine production in experimental neuroinflammatory disorders
(2013-09-04)
Glutamate excitotoxicity is involved in the pathogenesis of a variety of neurodegenerative disorders, including Alzheimer’s disease (AD), Parkinson’s disease (PD), and multiple sclerosis (MS). Kainic acid (KA), an analogue ...
New diagnostic approaches for venous thromboembolism and thrombophilia
(2020-05-15)
Background: Venous thromboembolism is a serious disease comprising both pulmonary embolism and deep vein thrombosis. Venous thromboembolism causes considerable mortality and morbidity, with residual symptoms such as pulmonary ...
Pharmacoepidemiologic studies of drug safety in pediatric chronic inflammatory disease
(2021-05-26)
Safety evidence for use of pharmaceutical drugs in children, including treatments for serious conditions such as chronic inflammatory diseases, is generally scarce. Off-label use is common and clinicians need to rely on ...
Autophagy and VPS34 as targets in anti-cancer therapy
(2021-08-20)
Autophagy (Greek for self-eating) is a cellular pathway that breaks down cytoplasmic components to fuel metabolism. In this way, autophagy maintains cellular homeostasis and sustains survival during stress conditions. In ...
Cytomegalovirus infection in vascular diseases and transplant rejection
(2012-05-11)
Human cytomegalovirus (HCMV) infects 60-100% of the adult population. It belongs to the Herpesviridae family and establishes latency within its host post primary infection. HCMV reactivation is dependent on inflammation ...