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New diagnostic approaches for venous thromboembolism and thrombophilia
(2020-05-15)
Background: Venous thromboembolism is a serious disease comprising both pulmonary embolism and deep vein thrombosis. Venous thromboembolism causes considerable mortality and morbidity, with residual symptoms such as pulmonary ...
Advancing the measurement of sedentary behaviour : classifying posture and physical (in-)activity
(2021-02-18)
Sedentary behaviour, defined by a sitting body posture with minimal-intensity physical activity, is an emergent public health topic. The time spent sedentary is associated with the incidence of non-communicable chronic ...
Periodontal conditions and treatment outcomes for subjects with diabetes mellitus : special emphasis on HbA1c levels and T-cells
(2016-11-25)
A two way relationship between periodontal disease (PD) and diabetes mellitus has previously been reported. This thesis was aimed to further analyze the influence of PD on blood glucose levels of subjects with type 2 ...
A 10-year follow-up of people with multiple sclerosis-aspects of disability and health, use of and satisfaction with care, and feasibility of cognitive behavioural therapy
(2014-11-21)
Background: Multiple sclerosis (MS) is a neuroinflammatory and neurodegenerative disease in the central nervous system which affects a number of life areas of the afflicted individual. Detailed knowledge is required on ...
Molecular mechanisms of transcriptional repression by the orphan receptor SHP
(2005-02-18)
SHP (Small Heterodimer Partner) is an atypical orphan member of the mammalian nuclear receptor family that consists of only a putative ligand-binding domain and thus cannot bind DNA. The aim of this thesis was to investigate ...
Identification of susceptibility genes for dyslexia
(2007-10-26)
Developmental dyslexia, also known as specific reading disability, is characterized by persistent difficulties in learning to read and spell in spite of adequate intelligence, education, social environment, and normal ...