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Clinical assessment of visual function with particular emphasis on testing methods for young children
(1998-03-27)
Research during the last decades has emphasised the importance of visual stimulation during the first months of life. It is consequently of great importance to identify children with subnormal vision as early as possible ...
Socially dependent avoidance learning : mechanisms of adaptive behavior
(2014-08-08)
Many aspects of human social behavior are likely to be shaped by punishment, threats of punishment, and avoidance of punishment. However, surprisingly little is known about the psychological mechanisms underpinning these ...
Lipids and autoimmunity in atherosclerosis and cardiovascular diseases
(2009-02-20)
Atherosclerosis is an inflammatory disease. The rupture of athrerosclerotic plaques is the major cause of severe cardiovascular disease (CVD), such as myocardial infarction (MI) and stroke. The stability of the plaque ...
Molecular epidemiology of tuberculosis
(2011-11-09)
Tuberculosis is a global epidemic, with one third of the world’s population estimated to be infected, around 9 million new active cases per year and close to 2 million deaths per year. Without adequate chemotherapy ...
Modulating chromatin by transcription and nucleosome turnover : a genome-wide study in fission yeast
(2015-12-10)
Eukaryotic DNA is wrapped around histone proteins to form a nucleosome, the basic
structural unit of chromatin. Multiple levels of chromatin organization are required to
compact DNA into chromosomes, to ensure an accurate ...
Inhibition of apoptosis by the Us3 protein kinase of herpes simplex virus 1
(2004-09-10)
The Herpes Simplex Virus 1 (HSV-1) US3 protein kinase is part of the anti-apoptotic arsenal that salvage HSV-1-infected cells from damage caused by different stimuli. The Us3 gene encodes a protein kinase that phosphorylates ...
Management of hemorrhagic complications associated with antithrombotic therapy
(2014-03-26)
Anticoagulants are used for the prevention and treatment of arterial and venous thromboembolism. Such therapy is always associated with an increased risk of bleeding. Intracranial hemorrhage is the most serious form of ...
Genetic determinants for susceptibility, progression and prognosis of prostate cancer
(2015-10-23)
Prostate cancer is the most commonly diagnosed form of non-skin cancer among men in developed countries. Although a large proportion of patients eventually die from the disease, many indolent tumors are found via prostate ...
Genetic and immunological mechanisms regulating neuroinflammation
(2010-10-27)
Multiple sclerosis (MS) is the most common neurological disorder in young adults and imposes both health and socioeconomic burdens on society. The cause and aetiology of MS are incompletely understood and current treatments ...
A novel drug and device in anesthesia : with focus on breathing and upper airway physiology
(2018-04-12)
Anesthesia-related airway complications are associated with hypoxia due to inability to secure or maintain the airway with subsequent insufficient ventilation and gas exchange. This thesis has explored the impact on airway ...