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Lipids and autoimmunity in atherosclerosis and cardiovascular diseases
(2009-02-20)
Atherosclerosis is an inflammatory disease. The rupture of athrerosclerotic plaques is the major cause of severe cardiovascular disease (CVD), such as myocardial infarction (MI) and stroke. The stability of the plaque ...
Hypospadias : analysis of a complex genetic disorder
(2007-08-10)
BACKGROUND: Hypospadias is a common inborn error of the male urethra that
involves an abnormally placed urethral opening. Its complex etiology is
largely elusive to date. Twin and familial studies highlight a genetic
background ...
Genomic profiling and gene-gene interaction in rheumatoid arthritis
(2015-08-20)
Complex disease is characterized by the interplay of multiple genetic and environmental
factors. Rheumatoid arthritis (RA) is a complex autoimmune disease with a pronounced
genetic component, mainly due to HLA-DRB1 gene, ...