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Genetic and immunological mechanisms regulating neuroinflammation
(2010-10-27)
Multiple sclerosis (MS) is the most common neurological disorder in young adults and imposes both health and socioeconomic burdens on society. The cause and aetiology of MS are incompletely understood and current treatments ...
Identification and functional characterization of irritable bowel syndrome (IBS) risk genes and variants
(2019-05-08)
As one of the most prevalent functional gastrointestinal disorders (FGIDs), irritable bowel syndrome (IBS) affects more than 10% of the general population worldwide with a higher prevalence in women. The primary clinical ...
HIV/HCV co-infection in Sweden : epidemiology, HCV treatment and the importance of IL28B gene polymorphism
(2013-11-14)
Liver disease, mainly due to hepatitis C virus (HCV) infection, is a leading cause of death in HIV positive patients with access to antiretroviral therapy (ART). HCV treatment, which can prevent long-term complications of ...
Serotonin system in Alzheimer’s disease : from a molecular and biomarkers perspective
(2016-10-24)
Serotonin, 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter with a wide range of biological functions. It contributes to the integrity, connectivity and function of the central nervous system (CNS). Here in this ...