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Fishing for small molecules to treat diabetes, from a beta cell perspective
(2023-10-27)
Maintenance of glucose homeostasis necessitates a precise control of insulin secretion. Pancreatic β cells sense fluctuation of blood glucose and secret insulin in response. However, functional β cell mass is decreased in ...
Atrial fibrillation and lifestyle factors with focus on physical activity and alcohol consumption
(2017-02-06)
studies of Swedish men (Cohort of Swedish Men) and women (Swedish Mammography Cohort). During 1997, 48,850 men who were born between 1918 and 1952 and lived in Västmanland and Örebro counties and 39,227 women who were born between 1914 and 1948 and lived...
Lifestyle and risk of abdominal aortic aneurysm
(2016-04-29)
Background: Lifestyle-related factors associated with abdominal aortic aneurysm (AAA) disease are very scarcely investigated in prospective design. Identification of such could provide better understanding of AAA epidemiology ...
Dietary phytoestrogens and esophageal cancer
(2013-11-21)
Esophageal cancer is the eighth most common invasive cancer in the world, a cancer with an increasing incidence and male predominance, and there is a great need for potential dietary prevention. The overall aim of this ...
Diet, lifestyle and chronic kidney disease
(2018-09-18)
Chronic kidney disease (CKD) is a rapidly growing public health problem, affecting 5-10% of the general population, and individuals with CKD have a substantially increased risk of morbi-mortality. Early detection and ...
A percentile approach to time-to-event outcomes
(2015-11-18)
Evaluating survival percentiles is a possible approach for the analysis of time-to-event outcomes that
moves the focus from risk to time, as the proportion of events is xed and the time by which that
proportion is ...
Risk factors for prostate cancer : analysis of primary data, pooling, and related methodological aspects
(2015-11-18)
Prostate cancer is the second most common cancer among men worldwide, yet its etiology remains
poorly understood. Obesity, on the other hand, is a prevalent but preventable medical condition that is
associated with ...
Diet and postprandial risk markers for complications in type 2 diabetes
(2020-02-21)
The period after a meal is complex with fluctuation in blood glucose, lipids and other metabolic responses. This may induce and/or increase inflammation and contribute to future development of diabetic complications. ...
Diet and risk of acute pancreatitis
(2016-05-11)
Acute pancreatitis is a sudden inflammation of the pancreas. It has a broad spectrum of clinical outcomes, ranging from mild and self-limiting to severe and potentially fatal, and is often followed by recurrent attacks ...
Cadmium exposure and risk of kidney effects and bone fractures : population-based studies in England and Sweden
(2013-09-20)
Cadmium (Cd) is a toxic metal with no beneficial biological function. The dissemination of cadmium to the surface environment, by industrial and agricultural practices, has led to increased human exposure. Food is the main ...