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Studies on colonoscopy and inflammatory conditions of the colon
(2023-10-20)
Background: Colonoscopy is a key investigative tool in inflammatory bowel disease and
diverticular disease, but elements of the pathogenesis, symptomatology and safety of
procedures in these two conditions remain unknown. ...
Eradication of Helicobacter pylori and gastric and oesophageal cancer : a systematic review and meta-analysis of cohort studies
(2017-04-28)
Background: Helicobacter pylori (H. pylori) is associated with an increased risk of gastric adenocarcinoma and gastric mucosa associated lymphoid tissue (MALT) lymphoma, and a seemingly decreased risk of oesophageal ...
Hepatic ischemia-reperfusion injury
(2020-02-28)
Hepatic ischemia-reperfusion (I/R) injury is a complex phenomenon occuring in response to interruption of the liver’s blood and oxygen supply and the subsequent restoration of blood flow and tissue oxygenation. Techniques ...
Cardiovascular disease in dementia
(2016-12-08)
The objective of this thesis was to characterize the burden of cardiovascular diseases in patients with dementia, their treatment and association with survival. Further, we aimed to explore whether cardiac structure in ...
Aspects of chemotherapy and photon and proton radiotherapy in patients with gastric cancer
(2015-02-13)
Gastric cancer remains a major health problem worldwide. The addition of chemotherapy
alone or in combination with radiotherapy to surgery in local gastric cancer improves
outcome. In more advanced stages, the optimal ...
Thioredoxin-1 in Alzheimer disease
(2015-11-05)
Oxidative stress is one of the earliest signs in Alzheimer Disease (AD) brain. In order to protect themselves against oxidative stress, neurons use antioxidants as a defense mechanism. Such an antioxidant is Thioredoxin-1 ...
Identification of novel tumor biomarkers for sensitivity to radio- and chemotherapy of lung cancer based on genomic analyses
(2013-10-01)
Lung cancer (LC) is one of the most common human cancers and the leading cause of cancer-related deaths worldwide. Treatment of LC is by surgery if the tumor is resectable, otherwise chemo- and/or radiotherapy (CT/RT) is ...
Exploring the role of vitamin E in Alzheimer’s disease : an epidemiological and clinical perspective
(2012-05-10)
Vitamin E, the main non-enzymatic lipophylic antioxidant in the human body, has a major role in protecting the brain from damage mediated by free radicals. The term vitamin E encompasses eight natural congeners (forms): ...
Experimental spinal cord injury : methodological and neuroimmunological contributions with some historical background
(2011-01-19)
Spinal cord injury (SCI) is an incurable neurotraumatic catastrophe that afflicts mostly young individuals with resultant functional impairment of varying degrees of severity. The single pharmacologic treatment option at ...