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Home-cage monitoring of activity patterns of laboratory mice
(2023-03-09)
The mouse, deriving from the house mouse, is the most common species used in biomedical research, and offers great advantages for researchers to study gene functions in a complex living organism. However, using animals as ...
On the possible use of oxysterols for the diagnosis and evaluation of patients with neurological and neurodegenerative diseases
(2005-02-25)
Oxysterols are monooxygenated derivatives of cholesterol with a unique ability to pass lipophilic membranes and are involved in a number of elimination pathways for cholesterol.
One of the major oxysterols in the ...
Implications of cholesterol and cholesterol-lowering therapy in Alzheimer's disease
(2007-08-06)
BACKGROUND: Alzheimer's disease (AD) is a severe neurodegenerative disease that mainly afflicts elderly persons, with a characteristic progressive decline of cognitive functions and dementia. It is believed that the majority ...
Artificial intelligence for breast cancer precision pathology
(2022-11-09)
Breast cancer is the most common cancer type in women globally but is associated with a continuous decline in mortality rates. The improved prognosis can be partially attributed to effective treatments developed for subgroups ...
Trends in population health in an era of increasing longevity
(2022-01-26)
In Sweden, the number of older adults over the age of 85 increased by 75% since 1990 while the number of centenarians has almost quadrupled. Rapid population ageing is a global phenomenon and projected to continue in almost ...