Search
Now showing items 1-5 of 5
Molecular mechanisms of alternative estrogen receptor signaling
(2003-04-18)
Estrogen is a key regulator of growth, differentiation and function in a broad range of target tissues, including the male and female reproductive tracts, mammary gland, bone, brain and the cardiovascular system. The ...
Dysglycaemia and cardiovascular disease. Aspects on screening, management, and prognosis
(2023-03-24)
Background: Dysglycaemia, in this thesis defined as impaired glucose tolerance (IGT) or type 2 diabetes (T2DM), is a major risk factor for cardiovascular disease (CVD). International guidelines recommend screening for ...
Modulation of nuclear receptor function by interacting proteins
(2007-08-21)
Nuclear receptors are a family of transcription factors involved in many
biological processes. They represent key potentials as therapeutic
targets for several clinical conditions such as diabetes, obesity,
cardiovascular ...
Genetic association studies of symptoms, comorbidity and outcome in bipolar disorder and schizophrenia
(2016-05-06)
Schizophrenia and bipolar disorder are complex brain disorders. Research has focused on
applying brain research to understand the etiology, as well as clinical research to improve
treatment, prognosis and progression. ...
Biology of lithium response in bipolar disorder : genetic mechanisms and telomeres
(2016-01-29)
Background: Bipolar disorder is a common, chronic and severe mental illness, causing
suffering and large costs. Lithium treatment is the golden standard and works in 2/3 of
patients, of which 50% are called lithium ...