Search
Now showing items 1-8 of 8
Modulation of nuclear receptor function by interacting proteins
(2007-08-21)
Nuclear receptors are a family of transcription factors involved in many
biological processes. They represent key potentials as therapeutic
targets for several clinical conditions such as diabetes, obesity,
cardiovascular ...
Chest wall sarcomas
(2010-03-05)
Aim: To evaluate initial symptoms and clinical features, diagnosis and delay
in osteosarcoma (OS), Ewing sarcoma (EWS) and chest wall chondrosarcoma
(CS). To assess treatment and identify prognostic factors in chest ...
A percentile approach to time-to-event outcomes
(2015-11-18)
Evaluating survival percentiles is a possible approach for the analysis of time-to-event outcomes that
moves the focus from risk to time, as the proportion of events is xed and the time by which that
proportion is ...
Hormonal regulation of HES-1 in breast cancer cells
(2008-05-21)
Hairy and Enhancer of Split homolog 1 (HES-1) is a transcriptional repressor belonging to the basic helix-loop-helix family of proteins, and has been shown to have a pivotal role as a regulator of neurogenesis, myogenesis ...
Chronic dysglycaemia and diabetes type : impact in critical illness and sepsis
(2022-09-19)
Diabetes is a common disease in the general population. Higher susceptibility to infection and increased morbidity can lead to severe illness and intensive care unit (ICU) admission. Glycated haemoglobin A1c (HbA1c), a ...
Role of cholesterol metabolism in hepatic steatosis and glucose tolerance
(2019-04-12)
The liver is the central organ for lipid, lipoprotein and glucose homeostasis, thus hepatic metabolic disturbances can predispose individuals to develop cardiometabolic disorders (CMD) such as atherosclerotic cardiovascular ...
Early diagnosis and risk stratification in patients with symptoms suggestive of acute coronary syndrome
(2018-10-25)
Background: Chest pain is one of the most common symptoms in patients presenting to the emergency department (ED). Identifying the minority of patients with an acute coronary syndrome (ACS) is a challenge. The introduction ...
Transfusion in critically ill patients : short- and long-term outcomes
(2017-02-23)
A blood transfusion is a common treatment for a range of conditions. Over 112 million blood transfusions are administered each year worldwide and many patients are thereby exposed to the possible risks associated with the ...