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Charting mast cell development in health and systemic mastocytosis
(2022-12-16)
Hematopoietic stem and progenitor cells give rise to various blood and immune cells, including mast cells. In adults, bone marrow hematopoietic stem cells give rise to mast cell progenitors. These mast cell progenitors ...
Stress, sleep, and allergy
(2010-10-15)
Allergic diseases have recently increased dramatically in the western
world, now affecting about 30% of the Swedish population. The reasons for
this increase are unclear, but some of the suspects are behavioral
factors, ...
Long-term clinical, histological and virological outcomes after sustained virologic response in patients with chronic hepatitis C
(2017-05-09)
Successful antiviral treatment of chronic hepatitis C (HCV), resulting in Sustained Virologic Response (SVR) has been shown to reduce the risk for liver related complications, hepatocellular carcinoma (HCC) and death. ...
Outcome after surgery for isthmic spondylolisthesis and degenerative disc disease
(2019-01-17)
Individuals with isthmic spondylolisthesis and lumbar degenerative disc disease may have low back and leg pain. Those with persistent symptoms non-responsive to conservative treatment are sometimes treated surgically. ...
Being in safe hands : the experiences of soft tissue massage as a complement in palliative care : intervention studies concerning patients, relatives and nursing staff
(2008-10-24)
The overall aim of this thesis was to explore how patients, relatives and
nursing staff experienced soft tissue massage in palliative care.
In order to explicate the experiences of soft tissue massage two
methodological ...
Leisure activities at old age and their influence on dementia development
(2009-04-20)
This thesis aims to describe the participation in leisure activities of elderly subjects and to detect their possible effect, if any, on the development of dementia. The data were derived from the Kungsholmen Project, which ...
Genetic studies of hypospadias
(2002-11-22)
Hypospadias is defined as an abnormal opening of the urethra on the underside of the penis. It is a frequently found malformation with an incidence of 3 per 1000 males. The aim of this thesis was to identify genetic and ...
New approaches for diagnostics and therapy of allergy to pets
(2015-04-01)
Allergic diseases have been described already in 900 AD but today allergic diseases have reached epidemic proportions. About 30% of the world population is affected. Typical allergic symptoms of the immune system’s reaction ...
A battle between host and pathogen : the innate immune response and enterovirus evasion strategies
(2014-09-18)
Infections with Coxsackieviruses are common and in most cases the infection is asymptomatic and efficiently cleared. On rare occasions, however, an infection can lead to severe diseases including myocarditis, hepatitis and ...
Bringing order to disorder : structural and functional analysis for development of strategies to target MYC
(2014-09-05)
Several cellular processes such as cell cycle progression, apoptosis, cell adhesion and motility, cell growth, angiogenesis and differentiation are regulated by the MYC (here MYCN and c-MYC) proto-oncogenes. Elevated ...