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Beyond Th1 and Treg : intestinal T helper cells in disease and tolerance
(2022-08-16)
The human intestinal tract is not only one of the largest organs by surface area in our bodies but also harbors the greatest number of immune cells. These cells are crucial for maintaining tolerance towards the various ...
Assessment of DNA damage, oxidative stress and inflammation in chronic kidney disease patients : and a clinical study of a dietary supplement
(2012-01-09)
Decreased kidney function is associated with higher levels of oxidative stress, inflammation and malnutrition. Chronic kidney disease (CKD) patients have a higher risk to develop cardiovascular disease, atherosclerosis and ...
Oral health in patients with chronic kidney disease
(2009-11-13)
Chronic kidney disease (CKD) is a complex disorder in which active intervention leads to longer survival expectancy. Oral diseases are complex disorders caused mainly by bacterial, fungal, or viral infections, where primary ...
Effects of mutations in lymphoid malignancy and immunodeficiency disease
(2017-03-31)
Mutations are responsible for causing various human diseases, including several types of cancer and immunodeficiency syndromes. They can either be involved directly in the pathogenesis of the disease or by influencing the ...
Toxicity and biocompatibility of nanoparticles, and studies on oxidative stress and DNA damage
(2015-05-11)
Oxidative stress is associated with several diseases, either as a cause or a consequence.
Chronic kidney disease (CKD) is one example of a disease in which elevated levels of
oxidative stress are frequently reported. ...
Obesity in childhood : psychosocial consequences and premature mortality
(2020-10-21)
Background: It is estimated that 91 million children worldwide will have obesity by 2025. Obesity in childhood is associated with increased risk of obesity in adulthood, psychosocial maladjustment, mental health problems, ...
DissolvIt : development and validation of a new in vitro dissolution apparatus for dry powder aerosols
(2022-05-09)
Today there are no recommended dissolution methods for use in the development of new inhalable drugs. In the absence of such tailored methods, standard dissolution test methods from oral- or skin administration routes are ...