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Ultrasound-guided in utero lentivirus transduction of the murine nervous system to investigate nervous system disorders
(2022-05-18)
Neurodevelopment is a highly dynamic process involving hundreds of molecular different cell types. Gain and loss of function studies provide valuable insight into the gene regulatory networks that orchestrate this morphological ...
Optimisation of dengue diagnostic tools in order to increase the knowledge of the pathogenesis
(2008-10-03)
Dengue fever (DF) is the most common global viral mosquito-borne infection, with 100 million estimated cases annually in tropical and subtropical areas. The dengue viruses (genus Flavivirus, Flaviviridae) occur in 4 serotypes ...
Aprotinin for reduction of bleeding and transfusions in patients on clopidogrel undergoing urgent coronary surgery
(2009-05-08)
Background: An increased proportion of patients with acute coronary syndrome undergo coronary surgery while treated with clopidogrel, an irreversible platelet ADP-receptor inhibitor. Clopidogrel in combination with aspirin ...
Characterization of dengue virus isolates from patients experiencing dengue fever, dengue hemorrhagic fever, and dengue shock syndrome
(2011-11-21)
The four serotypes of dengue virus (DENV) belong to the genus flavivirus, and have a positive sense, single-stranded RNA genome of ~11 kb. The DENVs cause the most common arthropod-borne viral disease in man with ~100 ...
Evaluation of patient related factors influencing outcomes after total hip replacement
(2014-04-30)
Background: Basic patient factors such as age, sex, and comorbidities are poorly understood in the context of re-operation rates and patient-reported outcome measures after total hip replacement (THR) surgery.
Aims: ...