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Evaluation of patient related factors influencing outcomes after total hip replacement
(2014-04-30)
Background: Basic patient factors such as age, sex, and comorbidities are poorly understood in the context of re-operation rates and patient-reported outcome measures after total hip replacement (THR) surgery.
Aims: ...
TGF-beta signaling in carcinogenic transformation of breast epithelial cells, using proteomics
(2008-09-18)
Transforming growth factor-beta (TGFbeta) is a key regulator of cell proliferation, death, migration and differentiation. One of the features of TGFbeta signaling is to inhibit tumor growth at the early stage of cancer but ...
Molecular and therapeutic aspects of breast cancer stem cells
(2015-08-10)
Breast cancer stem cells (BCSCs) are defined as a minor cellular component in the solid tumor, displaying mammary stem cell properties by expressing embryonic stem cell genes. They are usually undergoing self-.‐renewal ...
Optimization of HIV and tuberculosis co-treatment in Tanzania : drug-drug interactions and clinical outcomes
(2013-02-06)
Background: Sub-Saharan Africa has been greatly affected by the HIV epidemic, with an estimated 23.5 million people living with HIV/AIDS (PLWHA) residing within this region by the end of 2011, being the leading course of ...
Suicidal behaviour and healthcare use among refugees
(2021-11-10)
Background: Despite higher rates of mental disorders among refugees, there is limited evidence on their risk of suicidal behaviour (suicide attempt and suicide) and how such risk is influenced by differences in country-level ...
Identification of autoantigens in multiple sclerosis
(2023-01-04)
Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system in which cells from primarily the adaptive immune system infiltrate the brain and spinal cord, leading to inflammation and demyelination. ...