Search
Now showing items 1-8 of 8
Towards a cohesive understanding of the DNA damage response as a therapeutic target
(2022-06-01)
At the basis of the complexity that forms a human being is a highly regulated interplay of factors found at a molecular, cellular, and macroscopic level. Ever since we evolved to work this way, even the slightest dysregulation ...
Local anesthesia for pain relief after surgery
(2001-11-16)
Postoperative pain is a common problem in spite of increased awareness
among patients and healthcare professionals. The prevailing practice is
still to administer opiates, which have a good painrelieving potential
but ...
Asthma treatment in primary care : studies of variability and health economic aspects
(2009-05-15)
Background: Most asthma patients in Sweden are treated in primary care, but little is known about economic aspects of asthma treatment in that setting and about the regional variation in the use of antiasthmatics drugs and ...
Regulation of the ribosomal RNA transcription by c-MYC oncoprotein
(2006-11-30)
The transcription factor c-Myc is a key regulator of growth and proliferation. c-Myc levels are tightly controlled and deregulated c-Myc is often associated with human cancers. In our initial studies we observed that upon ...
CYP2C19 polymorphisms in drug metabolism and response
(2014-11-13)
Individuals vary widely in their response to drug treatment. After receiving doses of a drug that are recommended based on a population average, some patients could have an insufficient response, whereas others may experience ...
Novel biomarkers in regulating human dense connective tissue repair
(2022-11-18)
Painful and degenerative disorders of the musculoskeletal system pose a tremendous burden on the healthcare system. One main reason is the limited knowledge of the underlying key factors and pathways responsible for the ...
Cat and dog allergens : dispersal, exposure and health effects in childhood
(2002-11-21)
The association between pet ownership in childhood and subsequent asthma and sensitisation is very controversial. Intriguing but contradictory reports have caused considerable uncertainty in families who wish to avoid ...
Assessment of patients with late diagnosis and missed opportunities in the Swedish HIV-1 epidemic
(2016-02-22)
Discovered in 1983, with a possibility to diagnose since 1985, and with efficient treatment
existing now for two decades, HIV-1 still ranks among the top ten causes of death globally.
Approximately 40 million people are ...