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Novel biomarkers in regulating human dense connective tissue repair
(2022-11-18)
Painful and degenerative disorders of the musculoskeletal system pose a tremendous burden on the healthcare system. One main reason is the limited knowledge of the underlying key factors and pathways responsible for the ...
Studies on antioxidant and lipid lowering effects on human microcirculation
(2002-10-18)
In previous work from this laboratory, vital microscopy was successfully
used to study rnicrocirculatcry effects of hypercholesterolemia in a
rabbit model. Hypercholesterolemia caused a dramatic depression of the
blood ...
Individually tailored internet-based treatment for depression and comorbid conditions
(2018-12-21)
Background: Depression is a large societal problem. People suffering from depression are heterogeneous and have a high degree of comorbid conditions. Pharmacological treatment is widespread, but not effective for all ...
Characterisation of antibiotic-resistant Propionibacterium acnes from acne vulgaris and other diseases
(2006-05-12)
Propionibacterium acnes (P. acnes) is an anaerobic, Gram-positive bacterium that belongs to the normal microflora. The skin is the major habitat but it can also be found in other body regions. P. acnes plays an important ...
Burnout: a matter of impaired recovery?
(2012-01-13)
The general aim of this thesis work was to investigate physiological and subjective markers of recovery from stress in order to identify and discuss possible risk factors precipitating burnout, as well as factors related ...
B cell subsets in autoimmune disease
(2018-01-12)
B lymphocytes are a type of white blood cells, belonging to the adaptive arm of the immune system and involved in creating immunological memory. B cells function in the humoral immune system by secreting antibodies which ...
What makes cognitive behavior therapy work? An investigation of psychological and inflammatory processes
(2019-03-06)
Background: Common mental disorders (CMDs; anxiety disorders, depression, insomnia and stress-related disorders) cause significant suffering, reduced functioning and impaired quality of life. Cognitive behavior therapy ...
Basis for reclassification of nasopharyngeal carcinoma
(2012-03-22)
Nasopharyngeal carcinoma (NPC) shows broad differences in racial and geographical distribution, radiosensitivity, and a multifactorial etiology. This thesis aims to identify molecular biomarkers with potentially valuable ...
Role of syntaxin-11 and munc18-2 in lymphocyte cytotoxic granule exocytosis
(2016-08-18)
Mutations in genes required for the exocytosis of cytotoxic granules by NK cells and cytotoxic T lymphocytes are associated with early-onset familial hemophagocytic lymphohistiocytosis (FHL). In this project, we examined ...
Omega-3 fatty acid treatment in mild to moderate Alzheimer's disease : results from the OmegAD study
(2008-05-23)
Alzheimer's disease (AD) is a major public health concern in all
countries with an increasing prevalence. It is expected to quadruple by
the year 2047. AD is a progressive neurodegenerative disease with a
multifactorial ...