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Quantitative MRI biomarkers of neurodegeneration in multiple sclerosis
(2022-02-28)
Background: Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative disease that targets myelin in the brain and spinal cord. The corpus callosum connects the cerebral hemispheres and is composed of ...
Novel genetic associations with common variable immunodeficiency
(2016-05-11)
Common variable immunodeficiency (CVID) is the most frequently encountered primary immunodeficiency disorder in clinical practice and is a cause of significant morbidity and mortality for patients. The main clinical features ...
Cured but not well : long term survivorship after allogeneic haematopoietic stem cell transplantation
(2022-05-11)
Improved donor matching and supportive care have reduced short term complications after allogeneic haematopoietic stem cell transplantation (HSCT), leading to a growing number of survivors. However, despite being cured of ...
Apoptotic signaling in lung carcinoma cells : with focus on mechanisms of radioresistance
(2003-05-02)
In this thesis, IR-induced apoptotic signaling was studied in a panel of lung carcinoma cell lines. The goal was not only to achieve a better understanding of the process, but also to identify possible targets for ...
Allergy to pets : molecular approaches for improved diagnostics and vaccination
(2012-05-25)
Allergic diseases are a major health problem, affecting up to 30% of the population in affluent countries. Domestic pets such as cats, dogs and horses are among the most common agents of IgE-mediated allergies. Conventional ...