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Novel genetic associations with common variable immunodeficiency
(2016-05-11)
Common variable immunodeficiency (CVID) is the most frequently encountered primary immunodeficiency disorder in clinical practice and is a cause of significant morbidity and mortality for patients. The main clinical features ...
Assessment of dopamine and serotonin release in the non-human primate brain using PET
(2011-01-12)
The molecular imaging technique positron emission tomography (PET) allows for non-invasive examination of biochemical markers in the living brain. For over three decades PET studies have provided important insight into the ...
Development of novel 5-HT1B PET radioligands
(2019-05-15)
Positron emission tomography (PET) is a useful tool for studying the central nervous system (CNS) in living subjects. PET is a non-invasive imaging technique that can visualize biochemical process such as receptor-ligand ...
Erythrocyte amino acids in health and renal failure and their association to the IGF-I/IGFBP-1 axis
(1998-11-13)
Abnormalities in amino acids (AA) metabolism in uraemia have mainly been reported to occur in plasma and muscle. No investigation has been undertaken to evaluate the AA levels in plasma, muscle and red blood cells (RBC) ...
Chronic dysglycaemia and diabetes type : impact in critical illness and sepsis
(2022-09-19)
Diabetes is a common disease in the general population. Higher susceptibility to infection and increased morbidity can lead to severe illness and intensive care unit (ICU) admission. Glycated haemoglobin A1c (HbA1c), a ...
Effects of cigarettes, e-cigarettes and Swedish snus on vascular function
(2018-07-17)
Cigarette smoking is considered one of the leading causes of preventable morbidity and premature death worldwide. A large portion of this is attributable to cardiovascular disease such as ischemic heart disease and stroke. ...