Search
Now showing items 1-9 of 9
Exploring childhood apraxia of speech : speech and language profiles in 5-year-olds with suspected apraxia of speech or cleft palate
(2020-05-04)
Introduction and aims: Childhood apraxia of speech (CAS) is a speech sound disorder (SSD) lacking a quantifiable measure discriminating all cases of CAS from other SSDs. This project aimed at exploring CAS using different ...
Leukocyte activation in newborns in relation to prenatal stress
(2009-11-05)
The aim of this project is to describe the pattern of innate immunity responses at birth with focus on the recruitment of leukocytes such as eosinophils and neutrophils and their content of cathelicidin antimicrobial peptide ...
Experimental therapeutics against malignant mesothelioma : investigations in vitro
(2009-11-20)
Malignant mesothelioma is a tumour of the mesothelium, a specialized tissue found in the pleura, pericardium, peritoneum, and tunica vaginalis testis. The tumour has strong etiological links to asbestos, with a latency ...
Gestational age and size at birth and risk of esophageal inflammation and cancer
(2013-01-21)
Background: In a hypothesis generating study by my colleagues a 7-fold increase in the risk of esophageal adenocarcinoma (EAC) was found in a cohort of individuals born preterm or with a low birth weight. Preterm born ...
Periodontal conditions and treatment outcomes for subjects with diabetes mellitus : special emphasis on HbA1c levels and T-cells
(2016-11-25)
A two way relationship between periodontal disease (PD) and diabetes mellitus has previously been reported. This thesis was aimed to further analyze the influence of PD on blood glucose levels of subjects with type 2 ...
Beyond Th1 and Treg : intestinal T helper cells in disease and tolerance
(2022-08-16)
The human intestinal tract is not only one of the largest organs by surface area in our bodies but also harbors the greatest number of immune cells. These cells are crucial for maintaining tolerance towards the various ...
Possibilities of dried blood spots as a matrix in therapeutic drug monitoring of antiepileptic drugs in children
(2019-05-21)
For children with epilepsy, therapeutic drug monitoring (TDM) of antiepileptic drugs (AEDs) is essential for treatment. TDM monitoring requires two visits to a health care unit, first for collection of the blood sample ...
Strategies to optimize natural killer cell functions in the tumor microenvironment
(2023-10-13)
Immune cell-based therapies are currently changing the oncological treatment landscape worldwide. While genetically modified T cells have already been approved for clinical use in few hematological cancers, natural killer ...
Colonoscopic surveillance in familial colorectal cancer
(2014-10-03)
Colorectal cancer (CRC) is a disease with a high and rising incidence in the industrialized countries. It is the third leading cause of death among cancers in Sweden and the forth worldwide. Important etiological factors ...