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A novel single skeletal muscle cell in vitro motility assay : effects of aging and non-enzymatic glycosylation on myosin function
(2001-03-30)
The aims of this study were to develop a single skeletal muscle fiber in
vitro motility assay, and to employ the assay in order to study the
effects of aging and non-enzymatic glycosylation on the mechanical
properties ...
A safe road transport system : factors influencing injury outcome for car occupants
(2009-05-22)
Given that over a million people are fatally injured in road accidents
each year, the need for a systematic proactive approach is undeniable.
The Swedish Road Administration (SRA) has developed a model for a safe
road ...
Effects of cigarettes, e-cigarettes and Swedish snus on vascular function
(2018-07-17)
Cigarette smoking is considered one of the leading causes of preventable morbidity and premature death worldwide. A large portion of this is attributable to cardiovascular disease such as ischemic heart disease and stroke. ...
Studies on neurotrophins in inflammatory pulmonary diseases
(2010-01-15)
Asthma, sarcoidosis and chronic obstructive pulmonary disease (COPD) are
inflammatory pulmonary diseases, all being characterized by tissue
inflammation, tissue damage (airway remodeling) and loss of lung
function. In ...
Mammalian sperm flagella and cilia
(2009-04-17)
In mammals, both sperm flagella and cilia are axoneme-containing organelles. The sperm flagella are major parts of the spermatozoa that are male gametes produced in the testis from progenitor spermatogonia through a process ...
Children with low anorectal malformations and their parents : quality of life, physical and psychosocial function
(2018-10-31)
Anorectal malformations (ARM) are congenital anomalies affecting 1 in 3 000 births. The malformation varies from very minor to complex and can be divided in to low, intermediate, and high form of ARM. Children with a low ...
The many faces of IGF-1R from cell surface to the nucleus
(2009-05-01)
The IGF-1R is due to its implication in cancer an intensively studied subject of research. It is well known today that intracellular signals mediated by the IGF-1R play pivotal roles in tumorigenesis and cancer progression. ...
Toward safety promotion among road users : epidemiology and prevention of road traffic injuries in Iran
(2009-04-29)
Road traffic injuries (RTIs) are a major public health problem. Iran has
one of the highest RTI mortality and morbidity rates in the world. This
thesis aims to contribute understandings on fatal road-user patterns ...
Studies of overcoming acquired resistance : molecular mechanisms and development of novel drugs
(2014-05-19)
Chemotherapeutic agents have become widely applied for treatment of various types of malignancies. Drug resistance unfortunately remains as a major obstacle for the effectiveness of chemotherapy. Cancer drug resistance ...
Identification and characterization of a proteasome deubiquitinase inhibitor
(2014-01-10)
The 26S proteasome has emerged as an attractive therapeutic target in the treatment of cancers. Proteasome inhibitors have been shown to selectively kill cancer cells. The FDA approval of bortezomib for the treatment of ...