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Genetic studies in familial non-BRCA breast cancer
(2017-11-09)
an overrepresentation of endometrial cancer in the non-BRCA families with a 6.36 % proportion (CI 4.67–8.2) compared to the proportion in the general population in the reference years 1970 (3.07 %) and 2010 (2.64 %). The main finding of the study was the strong support...
Roles of SNAP-25 isoforms in activity-dependent long-term synaptic plasticity
(2019-05-28)
SNARE proteins, SNAP-25, syntaxin 1A and VAMP2 constitute the functional units which join together to form the core SNARE complex. The SNARE complex carries out the vital function of membrane fusion of intracellular vesicles ...
Toxicological studies of opiate-related death
(2007-04-25)
This thesis comprises studies on opiate overdose death, and focuses on
evaluation of toxicological characteristics including the possible
influence of abstinence and polydrug use for the fatal outcome.
In order to ...
Serodiagnostics of schistosomiasis using keyhole limpet hemocyanin (KLH) as antigen
(2006-04-20)
The diagnostics of invasive helminth infections is often indirect and based on antibody detection in serum specimens from infected individuals. This is the case in schistosomiasis (bilharzia) where no excreted eggs can be ...
Innate immunity in atherosclerosis : the role of pattern recognition receptors
(2014-10-15)
The pathogenesis of atherosclerosis is greatly influenced by the activities of both innate and adaptive immunity. Danger signals such as cholesterol crystals, oxidized LDL, and modified phospholipids may trigger sterile ...