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Medical decision-making in Alzheimer’s disease : a linguistic approach
(2018-10-26)
Objectives. To explore medical decision-making capacity (MDC) for research participation, in patients with Alzheimer's disease, using a linguistic approach and including comparable groups.
Materials and Methods. The ...
The functional organization of nuclear envelope proteins
(2014-09-05)
In eukaryotic cells, the nucleus is enclosed by a double lipid membrane, termed the nuclear envelope (NE). The NE consists of the outer nuclear membrane (ONM), the inner nuclear membrane (INM), the nuclear pore complexes ...
Drug resistance in acute myeloid leukemia : clinical and experimental studies
(2008-11-07)
The long-term result of chemotherapy in acute myeloid leukemia (AML) is
poor, even though a majority of AML patients initially respond to
chemotherapy and achieve complete remission (CR). Initially resistant
disease as ...
Prognostic markers in breast cancer associated with cell cycle control, proliferation and angiogenesis
(2004-03-05)
This thesis focuses on potential prognostic molecular breast cancer markers which are related to angiogenesis, proliferation or cell cycle control. A common denominator for all of the investigated markers in the thesis is ...
Local regulation of growth plate chondrocytes : molecular mechanisms and implications for longutidinal growth
(2010-10-08)
The regulation of linear growth is a complex and intriguing process that has the growth plate cartilage as its final target. Growth plate is a specialized cartilage localized in the end of the long bones between the ...
Muscle composition, reach, physical activity and botulinum toxin treatment in children with cerebral palsy
(2018-11-09)
Cerebral palsy (CP), the most common cause of movement disorders and physical disability in children all over the world, is caused by an injury to the developing brain. Although this injury is not progressive, the ...
Aetiology and infection susceptibility in neutropaenic patients
(2012-04-13)
Increasingly intensive antineoplastic regimes have been effective in the treatment for haematological malignancies, but as effective as it is in limiting neoplasm of the malignant cells, bystander damage occurs equally to ...
Ready to pull : force transmission during vascular development
(2019-12-17)
The transmission of mechanical forces controls a multitude of cellular processes such as migration, the formation of new organs, muscle contraction, and resistance to the continuous stress that blood flow exerts on the ...
Improving the quality of care for hip fracture patients : studies on fast-track to surgery and adverse events
(2018-05-16)
Hip fractures in the elderly are common and are associated with high comorbidity and mortality. Their care and treatment present challenges for nurses and other healthcare professionals and impose a substantial burden on ...
ROR1 : a novel receptor tyrosine kinase with unique therapeutic potentials in chronic lymphocytic leukemia
(2011-10-13)
Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of small B lymphocytes in blood, bone marrow, lymph nodes and other lymphoid tissues. CLL is the most common leukemia in the Western world. Despite ...