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Molecular studies on the autoantibody-mediated bone destruction in rheumatoid arthritis
(2017-09-14)
Autoantibody-positive rheumatoid arthritis (RA), also called seropositive RA, is characterised by the presence of anti citrullinated proteins antibodies (ACPA) that can be detected in blood several years before disease ...
Magnetic resonance imaging in chronic Achilles tendinopathy
(2004-03-05)
The main objective of this thesis was to evaluate and monitor the morphological response following treatment interventions in patients with chronic Achilles tendinopathy by using different MRI-techniques. For this purpose. ...
Voltage sensitivity of dopamine D2-like receptors
(2011-09-16)
G protein coupled receptors (GPCRs) mediate a multitude of responses serving hormonal, neurotransmitter, and sensory functions. These receptors are important drug targets; in fact, about 27 % of prescribed drugs are GPCR ...
Post-translational modification of estrogen receptor alpha and p53 in breast cancer cells
(2015-08-21)
Estrogen receptor α (ERα/ESR1) and tumor protein p53 (p53/TP53) signaling are aberrant and play important roles in breast cancer pathogenesis and evolution. ERα is highly expressed in the majority of breast cancers and is ...
Magnetic resonance imaging in the evaluation of chronic Achilles tendinosis
(2015-05-06)
The aim of the thesis was to evaluate magnetic resonance imaging (MRI) as an outcome in the evaluation of treatment in mid-portion Achilles tendinosis. Conventional MRI sequences, dynamic contrast enhanced MRI and measurement ...