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Communication and patient involvement in decision making : examples from consultations on atrial fibrillation
(2015-12-30)
Background: Further knowledge is needed regarding communication that occurs in practice between patients with atrial fibrillation (AF) and health professionals in consultations to understand the issue of patient involvement ...
Serotonergic mechanisms in atopic dermatitis
(2012-11-21)
Atopic dermatitis (AD) may be worsened by stress and anxiety. Serotonin (5-hydroxytryptamine; 5-HT) is an important mediator in stress and anxiety.
In the present thesis serotonergic mechanisms were studied in atopic ...
Genetic and functional studies on the thyroid hormone axis
(2008-10-24)
This thesis has two main parts. The first is based on the first three papers with a focus on understanding the etiology and pathogenesis of thyroid malfunction and its effects on different organs. The second is about gaining ...
Aspects on local recurrence of rectal cancer
(2009-04-09)
Rectal cancer is a common malignant disease in Sweden which is diagnosed in about 1,800 patients annually. Local failure, defined as residual or recurrent disease within the pelvis, is of major concern in rectal cancer ...
Bis-locked nucleic acids : a new tool for double helix invasion
(2015-08-18)
Deoxyribonucleic acid (DNA) is a macromolecule that contains the information for all living organisms to achieve important cellular processes such as growth and replication. DNA consists of two strands coiled around each ...
Erythropoietic protoporphyria clinical and epidemiological aspects
(2010-02-26)
Erythropoietic protoporphyria, EPP, is an inherited disease in which the main clinical manifestations are painful cutaneous sensitivity to intense light and liver disease which in some requires liver transplantation for ...
Epigenic regulation and posttranslational modification of human cytochrome P450s : focus on CYP2W1, CYP1A2 and CYP2C18
(2008-11-21)
The cytochrome P450 superfamily represents a very important group of
enzymes that are responsible for the metabolism of drugs as well as of
endogenous compounds. Many P450s are genetically polymorphic causing
important ...
Neonatal respiratory control : inspiration, inflammation and the prostaglandin E2 pathway
(2014-10-22)
Immature or deficient autonomic control is a common problem in infants born at a premature age, and is of central importance in apneas. The pre- and perinatal development of the brainstem neural circuits that control ...
The effectiveness and cost-effectiveness of cognitive behavioral therapy administered in group or via the internet for patients with irritable bowel syndrome
(2022-11-17)
Background: Irritable Bowel Syndrome (IBS) is a benign but debilitating disorder. It is the most commonly diagnosed gastrointestinal condition and affects between 7-21% of the world’s population. It is characterized by ...
Diet, lifestyle and chronic kidney disease
(2018-09-18)
Chronic kidney disease (CKD) is a rapidly growing public health problem, affecting 5-10% of the general population, and individuals with CKD have a substantially increased risk of morbi-mortality. Early detection and ...