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Bis-locked nucleic acids : a new tool for double helix invasion
(2015-08-18)
Deoxyribonucleic acid (DNA) is a macromolecule that contains the information for all living organisms to achieve important cellular processes such as growth and replication. DNA consists of two strands coiled around each ...
Toll-like receptor activation induced changes in dendritic cells
(2011-11-14)
Dendritic cells (DC) are professional antigen-presenting cells that act as a “bridge” between innate and adaptive immunity by the induction and subsequent orchestration of immune responses. The ligation of Toll-like receptors ...
HMGB1 in inflammation : secretion and function
(2008-11-07)
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterised
by progressive joint destruction. The inflammatory and joint destructive
processes in RA are mediated by resident synovial cells and cells
recruited ...