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Health financing systems and drug use in rural China
(2000-01-10)
This thesis aims to study the association between health-care financing systems and health-care consumers' drug use and health providers' prescribing in six Chinese counties. In a cross-sectional study, a multistage sampling ...
Transoesophageal and transthoracic recordings of mitral annulus motion
(2006-02-03)
Maximal systolic and diastolic velocities recorded from four sites of the mitral annulus motion (MAM) reflect left ventricular (LV) performance. This thesis focus on factors influencing M-mode derived velocities in healthy ...
Studies of histone modification systems in Schizosaccharomyces pombe
(2010-05-26)
The genetic information in every cell is carried in the DNA. In eukaryotes the DNA is wrapped twice around proteins called histones forming a repeating unit called the nucleosome, in fibers known as chromatin. Nucleosomes ...
Hidradenitis suppurativa : clinical studies with focus on evaluation
(2010-04-02)
Hidradenitis suppurativa (HS) is a chronic inflammatory disease of mainly
unknown aetiology which in most cases involves axillae or groins and that
can last for decades. In this thesis different clinical aspects of HS ...
Regulatory function of homeobox genes in the development of C. elegans
(2010-09-10)
The nematode worm Caenorhabditis elegans has been widely used as a genetic model for over 40 years to investigate developmental control genes. In this thesis, I studied the roles of several homeobox genes and a novel RNA ...
Brain opioid mechanisms in amphetamine induced behaviours
(2009-09-04)
Amphetamine abuse and dependence are global health problems, affecting large numbers of individuals. Despite extensive research efforts, there has been no evidence-based pharmacotherapy available for amphetamine dependence. ...
Influence of oxidative stress on aryl hydrocarbon receptor signaling
(2013-05-13)
The aryl hydrocarbon receptor (AHR), a multifunctional protein and a key regulator of drug metabolizing enzymes, belongs to the basic-helix-loop-helix (bHLH)/PAS (Per-Arnt-Sim) super-family of transcription factors. The ...
Insulin-like growth factor binding protein-3 : structure and function
(2007-11-02)
Insulin-like growth factor (IGF) -I and -II share structural homology with insulin. Their receptors and intracellular signaling are similar. Consequently, the biological actions of IGFs and insulin are overlapping. Insulin ...
From DNA to CBT : an investigation psychological therapy response and genetics
(2018-05-09)
Background: Social anxiety disorder, panic disorder, and major depressive disorder are common, disabling, and heritable disorders. The first line of treatment for all anxiety disorders and mild to moderate depression is ...
Malaria and polypeptides of Plasmodium falciparum at the infected erythrocyte surface
(2016-03-11)
Malaria is one of the top three most lethal infectious diseases in the world after tuberculosis
and HIV. The disease is caused by intracellular parasites of the genus Plasmodium spp. To
date, five Plasmodium spp have ...