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Studies of histone modification systems in Schizosaccharomyces pombe
(2010-05-26)
The genetic information in every cell is carried in the DNA. In eukaryotes the DNA is wrapped twice around proteins called histones forming a repeating unit called the nucleosome, in fibers known as chromatin. Nucleosomes ...
Genetics of systemic autoimmunity and comorbidities
(2020-11-26)
Sjögren‘s syndrome (SS) is a systemic autoimmune disease that typically affects the salivary and lacrimal glands leading to dry eyes and dry mouth, but the patients may also have systemic involvement. Most patients with ...
To kill two birds with one stone : targeting myeloid cells in cancers
(2015-05-08)
Cancer progression is often accompanied by chronic inflammation and severe impairment of the immune system. In recent years, therapies eliciting tumor-specific immunity have resulted in striking tumor control and survival ...