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Intracranial and intraocular grafting of fetal ventral mesencephalic and striatal tissues : neuronal survival and nerve growth characteristics
(1998-08-07)
Parkinson's disease is caused by degeneration of dopaminergic neurons in the ventral mesencephalon. Various animal models and clinical trials has shown that grafts of fetal ventral mesencephalic tissue can survive and ...
Being secure in insecurity : aspects of caring in the ambulance service
(2015-11-19)
Ambulance care focuses foremost on medical care and treatment. On the one hand the
ambulance service encounters persons suffering acute and severe physical illness or
injuries; conversely ambulance patients are described, ...
Molecular genetic studies of psoriasis susceptibility in 6p21.3
(2005-02-18)
Psoriasis is a common and chronic skin disease with multifactorial background. It affects approximately 2% of the Swedish population and is characterized by inflammatory and scaly lesions. The aetiology of psoriasis is not ...
Formation of the inhibitory KIR repertoire in human natural killer cells
(2012-01-23)
Natural killer (NK) cells are lymphocytes of the innate immune system that are able to secrete cytokines and detect virus infected and transformed cells. Contrary to T cells, NK cells recognize targets that lack expression ...
Mechanisms for pneumococcal meningitis and a new vaccine platform to raise a serotype-independent protection in the host
(2022-09-30)
Streptococcus pneumoniae is a highly relevant pathogenic bacterium, responsible for a large fraction of deaths and disease morbidity in the world. The pneumococcus remains the leading cause of life-threatening pneumonia, ...
New treatment strategies for growth failure caused by chronic inflammation in children
(2012-12-21)
Chronic inflammation during childhood often leads to impaired bone growth and reduced height in adulthood. Interleukin-1β (IL-1β), interleukin-6 (IL-6) and the tumour necrosis factor-α (TNF-α) are pro-inflammatory cytokines ...
Estrogen actions in the growth plate cartilage
(2020-03-24)
Estrogens may influence bone growth locally or systemically via the estrogen receptors alpha (ERα), beta (ERβ) and G protein-coupled estrogen receptor 1 (GPER-1). In Paper I, our study showed that the treatment of ...
Immune response and tumour cell detection in lymph nodes of head and neck cancer
(2018-10-18)
Many patients with head and neck squamous cell carcinoma present with regional spread to the cervical lymph nodes. Lymph nodes metastases are today the most important factor influencing both the treatment and outcome for ...
Aspects of chemotherapy and photon and proton radiotherapy in patients with gastric cancer
(2015-02-13)
Gastric cancer remains a major health problem worldwide. The addition of chemotherapy
alone or in combination with radiotherapy to surgery in local gastric cancer improves
outcome. In more advanced stages, the optimal ...
Ligand-activated proteolysis in nutrient signaling
(2004-10-22)
Cells respond to changing nutrient availability and make adjustments in physiological processes. Central for making proper adjustments is the ability to execute appropriate changes in patterns of gene expression.
The ...