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Molecular analysis of mutated P450c21 in congenital adrenal hyperplasia
(1998-05-14)
Defects in cytochrome P450c21 (21-hydroxylase, 210H) are the most common causes of congenital adrenal hyperplasia (CAH). This recessively inherited disorder demonstrates a wide spectrum of severity as a consequence of ...
Significance of adipose tissue characteristics for development of metabolic complications in obesity
(2014-11-14)
Background: Obesity is closely related to development of insulin resistance and dyslipidemia. Intrinsic properties of adipose tissue are also of great importance for obesity related comorbidity. The aim of this thesis was ...
Inflammatory biomarkers in ANCA-associated vasculitis
(2022-11-02)
Background: Antineutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is a heterogenous group of relatively rare and serious small vessel vasculitides, characterized by the presence of proteinase 3 (PR3) ANCA ...