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Illness, disease, sickness : clinical factors, concepts of pain and sick leave patterns among immigrants in primary health care : effects of different therapeutic approaches
(1997-09-12)
The outer framework for this thesis is the high rate of disability pensions among some immigrant groups in Sweden. The general aim for the research has been to understand the phenomena of illness, disease and sickness ...
Studies on cytokines and chemokines in cerebrovascular diseases and experimental cerebral ischemia
(2001-03-02)
Ischemic brain injury secondary to arterial occlusion, a major cause of stroke, is characterized by acute local inflammation, which involves the accumulation of polymorphonuclear neutrophils and other immune cells. Tissue ...
Tumor necrosis factor superfamily members CD137 and OX40 ligand in vascular inflammation
(2016-02-03)
Atherosclerosis, an inflammatory disease, is the major cause of cardiovascular disease - the main cause of death worldwide. T cells are central orchestrators of inflammation in atherosclerosis and critically depend on ...
Psoriasis : studies of phenotype at onset and of associated cardiovascular morbidity
(2005-08-12)
Psoriasis is a complex inflammatory skin disorder, affecting 2-3% of the population in the western world. The etiology of psoriasis is not yet known. However it is likely that its pathogenesis involves interplay between ...
Exosomes : nano-vesicles in immune regulation
(2008-05-23)
Nano-vesicles (30-100 nm) with an endosome-derived limiting membrane are
called exosomes. These are released from the cell when the endosome fuses
with the outer cell membrane. Exosomes from antigen presenting cells
(APC) ...
Infections in skin cancer
(2016-03-07)
The increasing prevalence of skin cancer results in that it will soon equal that of all other
cancers combined. Sun exposure is a well-known risk factor for its development, but
despite the growing public awareness of ...
Innate immunity in progressive multiple sclerosis
(2015-10-26)
Multiple sclerosis is (MS) is a chronic inflammatory autoimmune disease of central nervous system (CNS)
leading to demyelination, axonal damage and neurological handicap, often affecting young adults. A majority
of ...
Immunomodulation and its effector mechanisms in atherosclerosis
(2007-05-11)
Atherosclerosis is a disease of the arterial intima, characterized by
cholesterol deposition, inflammation and fibrosis. The pathogenesis of
atherosclerosis is related to both innate and adaptive immune responses,
and ...
Interaction-mediating sequences within class I viral fusion glycoproteins : their roles in viral infection and in applications
(2015-10-23)
Class I viral fusion glycoproteins facilitate fusion of the viral envelope with cell membranes and entry of the virus into the cell, through extensive short sequence-specific interactions. Regions mediating these interactions ...
Being born with congenital heart block : risk factors, growth and development
(2013-04-11)
Congenital heart block (CHB) is a rare but life-threatening disease associated with the presence of Ro and La autoantibodies in the mother of the child affected. CHB is one of the manifestations of neonatal lupus erythematosus ...