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Cardiovascular risk factors, diet and the metabolic syndrome
(2006-09-01)
The clustering of metabolic disturbances, referred to as the metabolic syndrome, is today at the centre of attention. The rationale for this focus is that the prevalence of the metabolic syndrome is increasing globally ...
Functional study of nuclear receptors and bile acids in the modulation of cholesterol homeostasis
(2013-10-08)
Cholesterol carries multiple biological functions in the body, and imbalanced cholesterol metabolism leads to atherosclerosis and cardiovascular diseases. The present thesis aims to extend the knowledge of cholesterol ...
Low back and neck-shoulder pain : work and heritability
(2008-11-14)
Low back pain (LBP) and neck-shoulder pain (NSP) represent a large public
health problem being common disorders that often lead to negative
consequences for the individual and large costs for Society. The main
goal of ...
Molecular mechanisms of amyloid self-regulation
(2012-11-01)
Amyloid is associated with both pathological protein deposits and the formation of
functional protein structures. Therefore, several strategies have evolved to control the
formation or inhibition of amyloid in vivo. In ...
Elucidation of the cell signaling pathways mediating innate immunity and host-pathogen interactions
(2019-03-14)
The ability to generate a robust immune response is integral to organismal homeostasis. Cells of the innate immune system are considered the first responders of immunity, and are therefore responsible for sensing both ...
To cut or not to cut? Episiotomy in vacuum extraction
(2022-04-05)
BACKGROUND AND AIMS: Obstetric anal sphincter injury (OASIS) may cause anal incontinence, as well as sexual dysfunction and psychological trauma. Mediolateral and lateral episiotomy have been shown to be protective against ...