Search
Now showing items 1-10 of 25
Aspects of hepatoduodenal trauma and fluid therapy in hemorrhagic shock
(2006-05-26)
Traumatic injury is the leading cause of death among young adults and children, accounting for 5 million deaths worldwide on an annual basis. In Sweden alone, 2500 individuals succumb to traumatic injuries yearly. Beyond ...
Pharmacokinetic and pharmacodynamic aspects on opioid administration, morphine and ketobemidone, in the pediatric population
(2012-10-23)
Opioids are the mainstay of the treatment of severe nociceptive pain in both children and adults. The studies in this thesis have focused on different aspects of opioid treatment in the pediatric population with special ...
Diabetes, physical activity and endometrial cancer
(2006-11-22)
Accumulating evidence suggests that hyperinsulinemia, in the context of insulin resistance, is associated with carcinogenesis. Physical activity is involved in the regulation of metabolic and hormonal pathways and is an ...
Children with low anorectal malformations and their parents : quality of life, physical and psychosocial function
(2018-10-31)
Anorectal malformations (ARM) are congenital anomalies affecting 1 in 3 000 births. The malformation varies from very minor to complex and can be divided in to low, intermediate, and high form of ARM. Children with a low ...
Studies on antioxidant and lipid lowering effects on human microcirculation
(2002-10-18)
In previous work from this laboratory, vital microscopy was successfully
used to study rnicrocirculatcry effects of hypercholesterolemia in a
rabbit model. Hypercholesterolemia caused a dramatic depression of the
blood ...
Clinical and genetic stratification of childhood psoriasis
(2015-04-29)
Psoriasis is a clinically heterogeneous and common disease affecting about 2-3% of the
population in Sweden. Twin and family studies have shown a strong and complex genetic
background in psoriasis. The strongest known ...
A fibrinogen-binding protein from Staphylococcus epidermidis
(2001-11-09)
Staphylococcus epidermidis, a coagulase negative staphylococci (CoNS), is a major component of human flora. It is one of the leading pathogens of nosocomial infections, particularly associated with foreign body infections. ...
On lumbar disc herniation : aspects of outcome after surgical treatment
(2017-04-28)
Knowledge about sciatica has grown immensely since the days of Hippocrates. Even so one must be impressed with the anatomical insights of those ancient times. Today we are able to describe at a molecular level how the ...
T cell signatures and modulation by regulatory T cells
(2019-03-22)
CD4 T cells are crucial coordinators of protective immune responses against microbes and tumors. However, immune responses misdirected towards self-antigens are the hallmarks of autoimmune diseases. Regulatory T cells ...
Natural killer cells in cancer : studies on migration and cytotoxicity
(2014-05-08)
The role of natural killer (NK) cells in cancer development has been studied extensively over the last four decades and the increasing knowledge on NK cell regulation has improved both safety and efficacy of treatment. ...