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Cryo-electron tomography of individual protein molecules
(2005-08-29)
Averaging methods of determining structure, such as X-ray diffraction, do not preserve information about the flexibility of molecules. Cryo-electron tomography allows us to reconstruct individual hydrated objects. The ...
Clinical studies of asthma phenotypes focusing on the role of the leukotrienes
(2006-11-24)
Inflammation in the airways in connection to asthma is a complex phenomenon and the mechanisms underlying the associated clinical symptoms involve the interaction of many different kinds of cells and mediators, giving rise ...
Thioredoxin and glutaredoxin systems under oxidative and nitrosative stress
(2017-03-16)
Our knowledge about reactive oxygen species (ROS) and reactive nitrogen species (RNS) has been changed from simple damaging molecules to redox signaling mediators. ROS/RNS mediated signaling is mainly based on the reversible ...