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Studies of high mobility group chromosomal protein 1 as a pro-inflammatory cytokine
(2005-05-27)
High mobility group box chromosomal protein 1 (HMGB 1) is a nuclear protein recently recognised as a pro-inflammatory cytokine with implications both in acute and in chronic inflammation. HMGB1 has been reported to act as ...
Procedure related pain and anxiety during bone marrow aspiration
(2010-04-14)
Bone marrow aspiration/biopsy (BMA) is a common procedure used to diagnose and follow up treatment in patients with haematological disorders. Procedures in these patients are often associated with some pain, discomfort and ...
The role of angiomotin in endothelial cell motility and cell-cell junction formation
(2005-08-26)
Clinical as well as pre-clinical data show that tumor growth can be restrained by inhibiting angiogenesis. We have been investigating the mechanism of action of angiostatin, an inhibitor of angiogenesis, in order to design ...
Genetic content of clinical pneumococcal isolates and its relation to disease outcome
(2009-09-30)
Streptococcus pneumoniae is a Gram-positive bacterium that can cause a wide range of diseases. These include otitis media, sinusitis, pneumonia and meningitis. It can, however, also cause asymptomatic carriage thereby ...
Mass spectrometric investigation of intoxications with plant-derived psychoactive substances
(2009-05-08)
The flora of the world contains many plants and fungi with stimulant, hallucinogenic and narcotic effects. For centuries, many of these have been used in initiation rites, physical and spiritual healing and rites of ...
Post-polio syndrome : physiotherapeutic analysis and interventions
(2013-01-24)
This thesis presents four studies focusing on outcomes of gait performance using gait analysis and/or the Six-minute-walk test (6MWT), in patients with post-polio syndrome (PPS). Further, resistance training in combination ...
Characterization of the Alzheimer's disease-associated clac protein
(2005-03-18)
Alzheimer's disease (AD) is the most prevalent form of dementia in
elderly people and is neuropathologically characterized by the presence
of extracellular senile plaques (SPs) in the brain. SPs are mainly
composed of ...
AIDS and endemic Kaposi's sarcoma development : comparison by histopathology, virology (HHV8/KSHV) and cytogenetics
(2005-08-30)
Kaposi’s sarcoma (KS) is a highly and abnormally vascularized tumor-like
lesion with spindle cells (SC) affecting the skin, lymphnodes and viscera
which is found in four different clinico-epidemiological forms as Classic
KS ...
Role of information technology on documentation and security of medical data
(2009-08-03)
Information technology (IT) is increasingly used in medicine, mainly for processing medical data. Understanding how IT affects the documentation and security of medical data and how users adapt IT systems can help to improve ...
Principles of transcriptional bursting in mammalian cells
(2023-05-22)
In mammalian cells, transcription occurs in discrete bursts leading to fluctuations in transcripts from expressed genes. Although this behavior was first reported not long after the discovery of messenger RNA (mRNA), the ...