Search
Now showing items 1-5 of 5
The functional role of the lateral olivocochlear system and mechanisms underlying sound condtioning
(2004-10-29)
Sound conditioning is a process induced by a low-level, non-damaging acoustic stimulus that provides protection against subsequent detrimental forms of acoustic trauma. Many hypotheses have been advanced to explain the ...
Kynurenic acid in psychiatric disorders : studies on the mechanisms of action
(2010-04-02)
Kynurenic acid, a metabolite of tryptophan along the kynurenine pathway, is an endogenous antagonist at NMDA- and α7* nicotinic acetylcholine- (α7*nACh) receptors. Previous studies have shown that elevated levels of ...
Endogenous kynurenic acid and schizophrenia : physiological and pharmacological aspects
(2006-05-12)
Kynurenic acid is a glutamate receptor antagonist with a preferential action at the glycine/Dserine site of the N-methyl-D-aspartic acid (NMDA) receptor. The compound is a metabolite of tryptophan and is synthesized in ...
Glutamatergic mechanisms in schizophrenia : role of endogenous kynurenic acid
(2005-11-18)
Kynurenic acid, a tryptohan metabolite synthesised in astrocytes, is an
endogenous antagonist at glutamate receptors, in particular it blocks the
glycine site of the (NMDA)-receptor, and at the a7* nicotinic receptor.
The ...
Interaction of genetic and environmental factors in childhood asthma and allergy
(2017-04-07)
Asthma and allergy are the most common chronic childhood diseases. Their occurrences are influenced by both genetic and environmental factors, although the underlying mechanisms are not fully understood. The overall aim ...