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Endogenous kynurenic acid and schizophrenia : physiological and pharmacological aspects
(2006-05-12)
Kynurenic acid is a glutamate receptor antagonist with a preferential action at the glycine/Dserine site of the N-methyl-D-aspartic acid (NMDA) receptor. The compound is a metabolite of tryptophan and is synthesized in ...
Modulation of the deubiquitinating system in viral infection, lymphoid cell activation and malignant transformation
(2007-11-16)
Most cellular proteins are affected by the conjugation of Ubiquitin (Ub),
which may regulate their stability, activity or localization. The family
of deubiquitinating enzymes (DUBs) removes Ub from conjugates and
regulates ...
Factors of importance for labor induction
(2018-09-14)
Background: What initiates the onset of labor is still not clarified, and it is debated whether expectant or active management is the best for the woman and the fetus. Active management means induction of labor (IOL) which ...