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Plasticity in the dopamine 1 receptor system : behavior and cell biological studies
(2004-09-10)
Dopamine is a key neurotransmitter in the brain, and has an important
modulatory role in the control of motor activity and cognitive processes.
Dysfunctions of the dopamine system have been implicated in several
neuro ...
The functional organization of nuclear envelope proteins
(2014-09-05)
In eukaryotic cells, the nucleus is enclosed by a double lipid membrane, termed the nuclear envelope (NE). The NE consists of the outer nuclear membrane (ONM), the inner nuclear membrane (INM), the nuclear pore complexes ...
On the role of dendritic cells in HIV-1 infection
(2004-11-26)
Dendritic cells (DCs) are antigen-presenting cells with the capacity to initiate primary T cell responses against pathogens such as HIV-1. In addition, DCs express the receptors required for HIV-1 infection and as DCs are ...
Interplay of chromatin remodeling, transcriptional regulation, and nuclear organization
(2015-05-12)
Transcription is regulated on different levels to ensure that genes are expressed at the correct time and in the amounts required. At the chromatin level, DNA is wound onto histone proteins, forming nucleosomes that influence ...