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On mapping the human somatosensory cortex : fMRI and PET imaging
(2004-08-26)
This work is based on experiments and simulations for the purpose of mapping the human somatosensory cortex. By using a combination of structural mapping (cytoarchitecture), connectivity mapping, functional mapping, and ...
Magnetic resonance imaging in chronic Achilles tendinopathy
(2004-03-05)
The main objective of this thesis was to evaluate and monitor the morphological response following treatment interventions in patients with chronic Achilles tendinopathy by using different MRI-techniques. For this purpose. ...
Novel aspects of the molecular biology of gastrointestinal stromal tumors
(2014-05-23)
The gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor in the gastrointestinal tract (GI). Historically, these tumors were commonly mistaken for myogenic and neurogenic masses, and then eventually ...
Translational investigations of novel and current antitumoral therapies in gastrointestinal stromal tumors
(2019-11-21)
Gastrointestinal stromal tumor (GIST) is the most common human sarcoma. Its incidence is around 10-15 per million person-years, translating into 150 new cases each year in Sweden. The molecular background for the absolute ...
Molecular mechanisms of imatinib resistance in gastrointestinal stromal tumor with focus on microRNAs
(2014-12-16)
Gastrointestinal stromal tumor (GIST) is mainly initialized by mutations in receptor tyrosine kinase genes KIT or PDGFRA. The development of imatinib, a small molecule inhibitor that targets these tyrosine kinase receptors, ...
To cut or not to cut? Episiotomy in vacuum extraction
(2022-04-05)
BACKGROUND AND AIMS: Obstetric anal sphincter injury (OASIS) may cause anal incontinence, as well as sexual dysfunction and psychological trauma. Mediolateral and lateral episiotomy have been shown to be protective against ...