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Pharmacogenetic and pharmacokinetic studies of cyclophosphamide : in cell, animal and human
(2004-01-29)
Cyclophosphamide (CPA) is widely used anti-cancer drug that has to be
catalyzed by the cytochrome P450 (CYP) enzyme 2B6 as well as some other
CYPs to exert its cytotoxic activity. A high degree of interindividual
variation ...
Clinical encounters with different illness realities : qualitative studies of illness and restructuring of illness meaning among two cultural groups of female patients in a multicultural area of Stockholm
(2003-09-19)
Background: Mental health care in Sweden encounters a multicultural population. Meaning given to illness may differ between patient, family and caregiver and this affects the clinical encounter and outcome of treatment.
The ...
Critical care in low resource settings
(2015-10-08)
Background: Critical care is the care of patients with immediately life-threatening disease or injury. The substantial global burden of critical illness is especially high in low resource settings. There is a striking lack ...
Psychosocial factors and prognosis in coronary heart disease
(2009-05-08)
Aim: This thesis aims to contribute to the better understanding of the
role of psychosocial factors in coronary heart disease (CHD) by analysing
(1) the relationship of income, anger expression and work stress with
prognosis ...
Diabetes among Turkish immigrants in Sweden : a study of prevalence and risk factors
(2013-08-28)
Background: Risk factors associated with the difference in susceptibility to diabetes in different ethnic groups are poorly understood. This thesis investigates differences in prevalence of, as well as risk factors for, ...
Imaging of the brain opioid system in amphetamine dependence
(2017-10-31)
Amphetamine dependence is a global health problem, often giving rise to severe medical and social complications in affected individuals. Unfortunately, there is still limited evidence for any specific treatment that would ...
Scarring and regeneration in the central nervous system
(2021-11-12)
In response to injury, tissues employ conserved reparative mechanisms to heal the damage and recover their function. The reparative success varies according to the organism, the tissue or organ, and the age of the specimen. ...