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Metabolism of melatonin : with focus on the influence of cytochrome P4501A2
(2004-01-09)
Melatonin (MT) regulates circadian rhythms. It is produced by
pinealocytes. Their function is regulated by light. MT enters the blood
stream by passive diffusion. It is primarily metabolized in the liver by
6hydroxylation ...
In vivo regulation of pancreatic beta cell function
(2018-03-01)
Pancreatic beta cells within the islets of Langerhans contribute to the regulation of glucose homeostasis by secretion of insulin, a hormone that stimulates the uptake of glucose by liver, muscle and fat tissue. In response ...
Biosynthesis and biological role of leukotrienes in B lymphocytes
(2006-11-27)
Leukotrienes (LT) are potent lipid mediators, synthesized from arachidonic acid (AA) upon cell activation. The essential enzyme for leukotriene biosynthesis is 5-lipoxygenase (5-LO), converting AA, through a two step process ...
Prostate cancer diagnostics : complications and ways to reduce unnecessary biopsies
(2014-12-29)
Introduction: Prostate cancer is the most common form of cancer among men in Sweden.
There has been a rapid increase in the incidence rate of prostate cancer following the
introduction of PSA testing and, today, more ...