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Specificity of neurotrophins in the nervous system : a genetic approach to determine receptor engagement by neurotrophins
(2004-01-02)
The classical neurotrophic factor hypothesis describes the neurotrophins as retrograde signalling factors supporting the survival of postmitotic neurons during the development. Knock-out mice for the neurotrophins and/or ...
Allergic inflammation in children with pet allergy and asthma : mechanisms, markers and clinical consequences
(2002-05-10)
Immunological background: Allergic inflammation is a multiple-step process with many actors, where eosinophils and the release of their granula proteins play an important role. The recruitment of eosinophils is a crucial ...
Critical care in low resource settings
(2015-10-08)
Background: Critical care is the care of patients with immediately life-threatening disease or injury. The substantial global burden of critical illness is especially high in low resource settings. There is a striking lack ...
Pelvic organ prolapse : aspects of etiology, symptomatology and outcome after surgery
(2009-04-17)
The objective of this thesis was to increase the understanding of
symptoms related to pelvic support defects, to study the influence of
non-obstetric risk factors for pelvic organ prolapse, to describe
short-term natural ...
Prostate cancer diagnostics : complications and ways to reduce unnecessary biopsies
(2014-12-29)
Introduction: Prostate cancer is the most common form of cancer among men in Sweden.
There has been a rapid increase in the incidence rate of prostate cancer following the
introduction of PSA testing and, today, more ...
CBT in primary care : effects on symptoms and sick leave, implementation of stepped care and predictors of outcome
(2018-02-01)
Background: Common mental disorders (CMDs) cause great individual suffering and high societal costs including long-term sick leave. Cognitive behavioural therapy (CBT) can effectively treat CMDs, but access to treatment ...
Trends in population health in an era of increasing longevity
(2022-01-26)
In Sweden, the number of older adults over the age of 85 increased by 75% since 1990 while the number of centenarians has almost quadrupled. Rapid population ageing is a global phenomenon and projected to continue in almost ...
Workplace-based sick leave prevention and return to work : exploratory studies
(2011-05-27)
Background: Earlier research have revealed risk factors for sick leave in the workplace, and thus the workplace
has become an important arena for sick leave prevention and return to work (RTW). Despite that, some of these ...